I run a full 57 system with standard ecu on the 999, the race ecu does alter the fueling but more at higher revs, its designed for track use and its rare you'll run at the same revs on the road, the downside of the race cu is that it can alter the fueling in the low/mid range making it more lumpy, no probs on a track but not pleasant in town. Some ecu's also allow higher rev limits before the limiter cuts in, once agin good on a track but how many times do you hit the limit on the road and has your engine been tuned for it.
I could do with a PC 111 on mine but the fueling is fine for what I use the bike for, Duc Glasgow set it up originally and Leeds did the last service and checked it. One day i'll get around to it....
the multi has a race ecu/termi's and I'm sure the original ecu gave better fueling but I want more HP on the multi so can live with it.